Thinking up tomorrow's medicine
In 2003, Caroline Le Guiner completed her PhD in Sciences, specializing in genetic and molecular biology particularly in the study of the regulation of alternative splicing. During this work, she was attached to the Cancer Research Institute in Nantes. After years of basic research on the cellular regulation mechanisms, she aspires to use the results of her work in a more concrete way. Thus, her great interest in medicine and patients led her towards applied research. Philippe Moullier, a medical doctor by training, who is also a researcher at INSERM and the founder of Nantes Gene Therapy Laboratory, accepted her in for her post doctorate work. 11 years later, she is still working in the same lab, where she is leading a gene therapy research program, whose goal is to develop drugs to treat a rare disease, Duchenne muscular dystrophy. A first clinical trial is expected to begin within a few months.
MELSORT, sustained by the “IGO” LABEX research program aims at using adoptive transfer of melanoma specific T cells selected through an original technology for the treatment of metastatic melanoma. A phase I/II clinical trial based on this therapy has been validated by the French authorities and will begin in Nantes in June 2015 including 17 patients with metastatic melanoma.
Effimune obtains regulatory approval for Phase I clinical trial in humans of its new immunomodulator FR104
[press release] Effimune announced that it had received the authorization from the Belgian regulatory authority, the FAMHP (Federal Agency for Medicines and Health Products) for a Phase I clinical trial of FR104, its drug candidate for controlling the regulation of the immune system. This double-blind randomized clinical trial will take place on 70 healthy volunteers (both men and women) over a period of 9 months, and will prepare the future development of FR104 in rheumatoid arthritis and kidney transplantation.
Meet them there.
Alongside BIO 2015, come and meet the companies members of our cluster experts in oncology during this event. Participation is free, sign up now to attend your place.
Research, Cancer, Ethics Bioinformatics, Plant science Mitochondrial medicine... Share your knowledge with international researchers and students from different countries and cultures.
The CMSB 2015 conference will be held in Nantes from Sept. 16th to Sept. 18th. The conference brings together computer scientists, biologists, mathematicians, engineers and physicists interested in a system-level understanding of biological processes.
The Atlanpole Biotherapies competitive cluster combines the expertise of laboratories, companies and technical departments for a public-private offer of services, comprehensive, relevant and competitive, in the value chain of bio-medicine from target discovery to clinical evaluation.
Our ambition is to become a reference center on an international scale for the development of diagnostic and therapeutic solutions in the field of biotherapies.
Atlanpole Biotherapies is a competitive cluster certified by the Ministry of Industry (July 2005).