CHARLES RIVER LABORATORIES

From small to large molecules and at every stage of drug development, Charles River Saint-Nazaire offers comprehensive capabilities to quantify and characterize drugs, their metabolites, and biomarkers across a wide range of animal and human biological matrices. These include plasma, whole blood, urine, excreta, bile, tears, cerebrospinal fluid (CSF), tissues, and more. Bioanalytical assays are primarily performed using liquid chromatography–tandem mass spectrometry (LC–MS/MS). This technology enables the rapid development of robust, sensitive, and highly specific methods for the quantification of a broad range of analytes. These include small molecules, biomarkers, peptides, proteins, monoclonal antibodies, LNPs, antibody–drug conjugates (ADCs—including both the antibody and conjugated components), and oligonucleotides.