CESTI IHU: innovative strategies of tolerance induction in the transplanted patient

3 October 2016

This research program, led by Dr. Sophie Conchon (CRTI – Inserm 1064 – ITUN) uses the specific immunological properties of the liver to induce tolerance in the recipient patient of an organ.

The liver is a vital organ that is the site of many metabolic functions.IHU

It is nourished by arterial blood but also portal venous blood, which is directly stemming from the digestive system and thus laden with food and bacterial antigens. The hepatic immune system is thus more inclined to tolerance, and better able to avoid a chronic inflammatory condition that would interfere with metabolic functions.

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